Novel Therapeutic Targets and Mechanisms for Treatment

Alzheimer's disease is a progressive neurodegenerative disease characterised histopathologically by the presence of plaques made primarily of Abeta amyloid and tangles composed primarily of hyperphosphorylated alphabetic character. There is currently no medication that would reverse the sickness, and everyone in this medical specialty is focused on treating the symptoms of the illness. With numerous new drugs beginning clinical trials, Alzheimer's treatment is entering a fresh new and exciting phase. Several of these new medicines are based on our most recent understanding of the pathologic process of Alzheimer's and are intended to either reduce or stop the disease's progression. Therapies aimed at some aspect of beta-amyloid accumulation, neurofibrillary tangle creation, and the inflammatory response are all being considered, as are the difficulties associated with each space. It's still unclear whether any of those approaches are unbeatable, but the great amount of work in each of those three domains gives some hope that a successful Alzheimer's treatment is on the horizon.

  • Neuroendocrine Pharmacology
  • Neurotransmitter-based targets
  • Deep brain stimulation
  • Super molecule aggregation
  • Neurotrophic factors

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