12^th International Conference on Alzheimer’s Disease & Dementia October 29-31, 2018 Valencia, Spain

Soraya L Valles graduated in Biological Science at the University of Valencia in 1985 and in 1996 she finished her PhD in the IIC Institute looking for astrogliogenesis during brain development. In 1997 she spent three years at Hallamshire Hospital, Sheffield, UK. She was working in inflammation and regulation of IL-1 and IL-1 receptor. In 2000 she returned to Spain at Department of Physiology, Faculty of Medicine in University of Valencia until now. She is working in toxicity in developmental and neurodegenerative disease (such as Alzheimer’s disease) looking for oxidative stress and inflammation mechanisms.

Neurodegenerative disease, Inflammation mechanisms, Alzheimer’s disease

Experienced manager with a demonstrated history of working in care homes for the elderly who suffer Alzheimer’s disease and dementia. A specialist in the field of Alzheimer care with relentless curiosity, intellectual and creative personality. Strong professional with a Master's degree in Psychology from SWPS University of Social Sciences and Humanities, BA (Hons) degree in Tourism Management from Bournemouth University and course in Psychology of Addiction from Oxford University. Member of British Psychological Society BPS.

Alzheimer care

Mourad Tayebi is Associate Professor in Biomedical Sciences at the School of Medicine, Western Sydney University, AUSTRALIA. Dr. Tayebi is an international expert in the field of PROTEIN MISFOLDING DISEASES, with specific focus on investigating the molecular mechanisms underlying pathogenic protein misfolding and characterizing the misfoldome associated with these disorders. Dr. Tayebi’s team is very active in the development of early blood diagnostic test screen for Alzheimer and effective therapies for neurodegenerative diseases.

Protein misfolding diseases, Blood Diagnostic Test, Neurodegenerative Diseases

TY Chang shares the same laboratory with his wife and long-term collaborator Dr. Catherine Chang at Geisel School of Medicine at Dartmouth. They have been working on cholesterol metabolism research for more than four decades. The Changs and their colleagues did ground breaking work by identifying the gene that encodes the cholesterol storage enzyme acyl-CoA:cholesterol acyltransferase 1 (ACAT1/SOAT1). For this work, Dr. T.Y. Chang received a MERIT award from NIH, USA. More recently, the Chang lab at Dartmouth demonstrated ACAT1 as a potential target for treating several human diseases, including Alzheimer’s disease and Niemann-Pick type C disease.

Niemann-Pick type C disease, Alzheimer’s disease, cholesterol homeostasis.

Catherine Chang is the co-Principal Investigator of the Chang laboratory at Geisel School of Medicine at Dartmouth, with her husband and long-term collaborator Dr. T.Y. Chang as the PI. They have been working on cholesterol metabolism research for more than four decades. The Changs and their colleagues did ground breaking work by identifying the gene that encodes the cholesterol storage enzyme acyl-CoA:cholesterol acyltransferase 1 (ACAT1/SOAT1). Subsequently, they performed extensive functional analysis of the enzyme. More recently, they demonstrated ACAT1 as a potential target for treating several human diseases, including Alzheimer’s disease and Niemann-Pick type C disease.

Alzheimer’s disease and Niemann-Pick type C disease, cholesterol storage enzyme.